Junji Kobayashi Selected Research

Hyperlipoproteinemia Type III (Broad Beta Disease)

1/2015	Autosomal recessive hypercholesterolemia: a mild phenotype of familial hypercholesterolemia: insight from the kinetic study using stable isotope and animal studies.
2/2012	Altered metabolism of low-density lipoprotein and very-low-density lipoprotein remnant in autosomal recessive hypercholesterolemia: results from stable isotope kinetic study in vivo.
12/2011	A novel type of familial hypercholesterolemia: double heterozygous mutations in LDL receptor and LDL receptor adaptor protein 1 gene.
5/2011	Impact of bezafibrate and atorvastatin on lipoprotein subclass in patients with type III hyperlipoproteinemia: result from a crossover study.
6/2005	Type III hyperlipoproteinemia exaggerated by Sheehan's syndrome with advanced systemic atherosclerosis: a 28-year clinical course.
10/2004	Detailed analysis of serum lipids and lipoproteins from Japanese type III hyperlipoproteinemia with apolipoprotein E2/2 phenotype.

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Junji Kobayashi Research Topics

Disease

12	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 09/2003
12	Atherosclerosis 09/2019 - 07/2004
12	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 04/2016 - 02/2002
10	Type 2 Diabetes Mellitus (MODY) 01/2019 - 10/2003
8	Dyslipidemias (Dyslipidemia) 09/2021 - 04/2007
7	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2016 - 05/2006
7	Hyperlipidemias (Hyperlipidemia) 01/2014 - 06/2002
6	Coronary Artery Disease (Coronary Atherosclerosis) 01/2018 - 11/2006
6	Hyperlipoproteinemia Type III (Broad Beta Disease) 01/2015 - 10/2004
5	Hypertriglyceridemia 01/2012 - 05/2005
4	Glucose Intolerance 03/2018 - 05/2010
4	Hypertension (High Blood Pressure) 08/2016 - 09/2005
4	Inflammation (Inflammations) 08/2009 - 09/2003
4	Coronary Disease (Coronary Heart Disease) 04/2007 - 02/2002
3	Diabetes Mellitus 02/2015 - 12/2002
3	Xanthomatosis (Xanthoma) 01/2015 - 06/2005
3	Homozygous Familial Hypercholesterolemia 01/2015 - 02/2012
3	Insulin Resistance 01/2013 - 03/2007
2	Hyperlipoproteinemia Type I (Lipoprotein Lipase Deficiency, Familial) 11/2020 - 01/2012
2	Anemia 01/2015 - 01/2009
2	Hypercholesterolemia 01/2015 - 12/2011
2	Obesity 01/2013 - 06/2008
2	Neoplasms (Cancer) 01/2013 - 01/2013
2	Hyperlipoproteinemia Type V 01/2012 - 06/2005
2	Fatty Liver 11/2009 - 01/2009
2	Aortic Valve Stenosis (Aortic Stenosis) 05/2009 - 12/2006
2	Cholesteryl Ester Transfer Protein Deficiency 04/2009 - 02/2008
2	Carotid Artery Diseases 02/2007 - 02/2002
2	Myocardial Infarction 09/2005 - 01/2005
2	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 11/2004 - 12/2002
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2021
1	Arteriosclerosis 09/2021
1	Non-alcoholic Fatty Liver Disease 12/2019
1	Body Weight (Weight, Body) 01/2019
1	Chronic Renal Insufficiency 03/2017
1	Stroke (Strokes) 03/2017
1	Abdominal Obesity 08/2016

Drug/Important Bio-Agent (IBA)

13	LipidsIBA 10/2021 - 10/2003
13	Triglycerides (Triacylglycerol)IBA 10/2021 - 10/2004
12	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2022 - 10/2003
12	Lipoproteins (Lipoprotein)IBA 01/2018 - 02/2002
11	oxidized low density lipoproteinIBA 01/2018 - 02/2002
11	Glucose (Dextrose)FDA LinkGeneric 05/2017 - 11/2004
9	LDL CholesterolIBA 09/2021 - 02/2002
9	CholesterolIBA 07/2011 - 10/2004
8	HDL CholesterolIBA 01/2012 - 09/2003
7	LDL Receptors (LDL Receptor)IBA 01/2015 - 01/2005
7	LDL Lipoproteins (beta Lipoproteins)IBA 01/2015 - 01/2005
5	AdiponectinIBA 01/2019 - 02/2007
5	Heparin (Liquaemin)FDA LinkGeneric 04/2016 - 10/2003
5	ApolipoproteinsIBA 11/2009 - 10/2004
4	Lipase (Acid Lipase)FDA Link 09/2019 - 11/2006
4	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2004
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2016 - 01/2005
4	Insulin (Novolin)FDA Link 01/2013 - 12/2002
3	Atorvastatin (Lipitor)FDA Link 01/2022 - 05/2005
3	colestimideIBA 04/2016 - 05/2005
3	Proteins (Proteins, Gene)FDA Link 01/2015 - 04/2007
3	Proprotein Convertase 9IBA 09/2014 - 07/2011
3	VLDL LipoproteinsIBA 02/2012 - 01/2009
3	Apolipoproteins E (ApoE)IBA 11/2009 - 10/2004
2	pitavastatin (itavastatin)FDA Link 01/2022 - 01/2013
2	6- ((4- ethylphenyl)methyl)- 3',4',5',6'- tetrahydro- 6'- (hydroxymethyl)spiro(isobenzofuran- 1(3H),2'- (2H)pyran)- 3',4',5'- triolIBA 01/2019 - 05/2017
2	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2019 - 05/2017
2	Ezetimibe (Zetia)FDA Link 04/2016 - 02/2012
2	HDL LipoproteinsIBA 01/2015 - 01/2012
2	IsotopesIBA 01/2015 - 02/2012
2	ChylomicronsIBA 01/2012 - 07/2011
2	BezafibrateIBA 07/2011 - 05/2011
2	Fenofibrate (CiL)FDA LinkGeneric 07/2011 - 04/2006
2	AdipokinesIBA 07/2011 - 01/2011
2	Apolipoprotein E2IBA 05/2011 - 10/2004
2	AlbuminsIBA 01/2009 - 09/2005
2	Cholesterol Ester Transfer ProteinsIBA 02/2008 - 11/2006
2	Apolipoprotein E3IBA 02/2008 - 06/2002
1	red yeast riceIBA 09/2021
1	Lovastatin (Mevacor)FDA LinkGeneric 09/2021
1	(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA 11/2020
1	EnzymesIBA 11/2020
1	Methionine (L-Methionine)FDA Link 12/2019
1	Choline (Choline Chloride)IBA 12/2019
1	salicylhydroxamic acid (SHAM)IBA 12/2019
1	Sodium-Glucose Transport ProteinsIBA 01/2019
1	Hemoglobins (Hemoglobin)IBA 01/2019
1	Uric Acid (Urate)IBA 01/2019
1	Blood Glucose (Blood Sugar)IBA 01/2019
1	Angiopoietin-Like Protein 8IBA 03/2018
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2018
1	low density lipoprotein inhibitorIBA 01/2018
1	GPI-Linked ProteinsIBA 01/2018
1	SodiumIBA 05/2017
1	Pharmaceutical PreparationsIBA 04/2016
1	anagliptinIBA 04/2015

Therapy/Procedure

7	Therapeutics 04/2016 - 01/2005
3	Drug Therapy (Chemotherapy) 01/2013 - 05/2009
3	Kampo Medicine (Kampo) 01/2013 - 01/2013
1	Diet Therapy (Therapy, Diet) 09/2021
1	Acupuncture Points (Acupuncture Point) 12/2019
1	Acupuncture Therapy 12/2019
1	Percutaneous Collagen Induction 12/2019